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. Author manuscript; available in PMC: 2024 Jan 19.
Published in final edited form as: Cell. 2023 Jan 4;186(2):327–345.e28. doi: 10.1016/j.cell.2022.12.013

List of statistical analyses. Related to Figures 1–7.

Figure Panel Statistical Test Post-hoc Test Planned Comparison Sample Size
1H one-way ANOVA Dunnett’s test vs NELFB ≥9
2H two-tailed unpaired t-test N/A N/A ≥10
2J two-tailed unpaired t-test N/A N/A ≥10
2M two-tailed unpaired t-test N/A N/A 10
2P one-way ANOVA Dunnett’s test vs CFP-LacI (“-”) ≥13
3D two-tailed unpaired t-test N/A N/A 100
3F one-way ANOVA Dunnett’s test vs control siRNA (ctrl.) 3
3J one-way ANOVA Dunnett’s test vs NT control 3
3L one-way ANOVA Dunnett’s test vs First bin 207
3N one-way ANOVA Dunnett’s test vs non-targeting gRNA (NT) (left plot) or vs siRNA control (ctrl) (right plot) 63
4F one-way ANOVA Dunnett’s test vs no IDR control ≥9
4I one-way ANOVA Dunnett’s test vs no IDR control 10
4L one-way ANOVA Dunnett’s test vs mCherry only (no IDR control) 20
5A one-way ANOVA Dunnett’s test vs partitioned IDRs All IDRs, 14088; Extract IDRs, 3955; partitioned IDRs, 200; and Excluded IDRs, 200
5G one-way ANOVA Dunnett’s test vs CTR9 IDR wildtype 10
5I one-way ANOVA Dunnett’s test vs SPT6 IDR wildtype 10
5K one-way ANOVA Dunnett’s test vs no IDR control 20
5M one-way ANOVA Dunnett’s test vs ABABA ≥12
5P one-way ANOVA Dunnett’s test vs no IDR control ≥12
5Q one-way ANOVA Dunnett’s test vs no IDR control ≥10
5S one-way ANOVA Dunn’s test vs no IDR control no IDR= 20; WT= 20; blocky= 16
5T one-way ANOVA Dunnett’s test vs WT or vs no IDR no IDR= 14; WT= 16; Blocky= 16
6C one-way ANOVA Dunnett’s test vs no IDR control 15
6F two-tailed unpaired t-test N/A charge pattern vs no pattern 13
6I two-tailed unpaired t-test N/A charge pattern vs no pattern 8
7C one-way ANOVA Dunnett’s test vs WT MED1 IDR ≥10
7G left one-way ANOVA Dunnett’s test vs WT MED1 IDR 20
7G middle one-way ANOVA Dunnett’s test vs WT MED1 IDR 20
7G right one-way ANOVA Dunnett’s test vs WT MED1 IDR 10
7I one-way ANOVA Dunnett’s test vs WT MED1 IDR 3
7K one-way ANOVA Dunnett’s test vs WT MED1 IDR 5
7N left one-way ANOVA Dunnett’s test vs no IDR control 20
7N middle one-way ANOVA Dunnett’s test vs no IDR control 20
7N right one-way ANOVA Dunnett’s test vs no IDR control 10
7P one-way ANOVA Dunnett’s test vs NC 3
7R one-way ANOVA Dunnett’s test vs NC 5