Fig. 6.

Developmental synapse remodeling of DD motor neurons. a) Illustration of DD neuron morphology and connectivity in early and mid-L1 larvae (left) and late L2 to adults (right). b) Schematics of the ventral cord locomotor circuit in young L1s (left) and adults (right). In L1s DA/DB cholinergic neurons excite both dorsal body muscles (curved light brown shade) and DD neurons, which inhibit ventral body muscles. In adults VA/VB cholinergic neurons excite both ventral body muscles and DD neurons, which inhibit dorsal body muscles. c) Graphic summary of major regulators of DD synapse remodeling (see main text for detailed description and references). Nomarski images and art drawing are credited to Eugene Jennifer Jin.