Table 2.
Variable | Overall | NYHA class I | NYHA class II to IV | P-value |
---|---|---|---|---|
(N=100) | (N=39) | (N=61) | ||
CMR parameters | ||||
Heart rate, bpm | 73 (65–83) | 71 (63–81) | 76 (67–86) | 0.068 |
LV end-diastolic volume, ml | 156 (135–184) | 170 (140–197) | 152 (133–178) | 0.14 |
LV end-systolic volume, ml | 64 (49–85) | 65 (52–84) | 63 (45–87) | 0.62 |
LV ejection fraction, % | 60 (51–66) | 61 (53–65) | 58 (50–66) | 0.55 |
LV mass index, g/m2 | 58 (49–66) | 61 (52–69) | 56 (47–65) | 0.093 |
LV GLS, % | –21.8 (–24.0 to –18.1) | –22.6 (–24.5 to –19.5) | –20.9 (–23.8 to –17.5) | 0.14 |
Left atrial volume index, ml/m2 | 42 (34–54) | 42 (35–50) | 41 (34–56) | 0.98 |
LARS, % | 36 (29–45) | 41 (34–47) | 35 (25–41) | 0.004 |
Pericardial effusion | 22 (23%) | 8 (21%) | 14 (25%) | 0.66 |
Presence of late gadolinium enhancement | 20 (21%) | 6 (15%) | 14 (25%) | 0.26 |
RV end-diastolic volume, ml | 154 (129–185) | 155 (129–193) | 153 (129–179) | 0.64 |
RV end-systolic volume, ml | 74 (55–94) | 76 (55–93) | 74 (57–94) | 0.59 |
RV ejection fraction, % | 52 (47–59) | 55 (49–61) | 51 (45–57) | 0.051 |
RV mass, g | 20 (16–25) | 22 (16–28) | 19 (14–23) | 0.078 |
RV GLS, % | –27 (–31 to –22) | –28 (–32 to –23) | –26 (–31 to –21) | 0.23 |
RA volume index, ml/m2 | 45 (33–58) | 44 (35–50) | 47 (33–60) | 0.12 |
Echocardiographic parameters | ||||
Diastolic function | 0.16 | |||
Normal diastolic function | 56 (59%) | 26 (68%) | 30 (53%) | |
Indeterminate diastolic function | 14 (15%) | 6 (16%) | 8 (14%) | |
Diastolic dysfunction | 25 (26%) | 6 (16%) | 19 (33%) | |
PASP, mmHg | 28 (22–35) | 27 (23–31) | 30 (22–39) | 0.30 |
Median (IQR); n (%). CMR: cardiac magnetic resonance; IQR: interquartile range; LARS: left atrial reservoir strain; LV: left ventricular; GLS: global longitudinal strain; PASP: pulmonary artery systolic pressure; RA: right atrial; RV: right ventricular; TR: tricuspid regurgitation.