Skip to main content
. Author manuscript; available in PMC: 2023 Feb 9.
Published in final edited form as: Free Radic Biol Med. 2021 Apr 18;169:224–237. doi: 10.1016/j.freeradbiomed.2021.04.022

Fig. 3. Outcome of SOD and Catalase enhancement depends on cellular redox state.

Fig. 3.

In cells with high steady-state levels of ROS, either due to a specific cellular metabolism or trigger-induced, overexpression of Sod and catalase rescues redox-balance and reduces proliferation to healthy levels. In contrast, the reduction of proliferation stemming from their overexpression in cells with healthy redox-state negatively impacts survival.