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. 2023 Jan 26;14:1061284. doi: 10.3389/fpsyt.2023.1061284

TABLE 6.

The sensitivity, specificity, positive predictive, and negative predictive values (NPVs) of the HbO2 cut-off point for differentiating healthy controls from schizophrenia patients at the right orbitofrontal cortex during the verbal fluency test (VFT).

HbO2 cut-off point (Unit: μ M) Sensitivity Specificity Positive predictive value Negative predictive value Correctly classified Youden’s index
0.088 0.85 0.64 0.85 0.65 0.70 0.49
0.102 0.85 0.65 0.85 0.65 0.71 0.50
0.112 0.85 0.65 0.85 0.66 0.71 0.51
0.121 0.85 0.66 0.85 0.66 0.72 0.51
0.130 0.85 0.67 0.86 0.67 0.73 0.52
0.136 0.85 0.68 0.86 0.67 0.73 0.53
0.155 0.85 0.69 0.86 0.67 0.74 0.54
0.169 0.85 0.70 0.87 0.67 0.75 0.55
0.208 0.85 0.71 0.87 0.67 0.75 0.56
0.209* 0.85 0.72 0.88 0.68 0.76 0.57
0.212 0.83 0.72 0.88 0.64 0.75 0.55
0.213 0.81 0.72 0.87 0.62 0.75 0.53
0.250 0.79 0.72 0.87 0.60 0.74 0.51
0.265 0.77 0.72 0.87 0.57 0.73 0.48
0.280 0.74 0.72 0.86 0.55 0.73 0.46
0.291 0.74 0.73 0.86 0.55 0.73 0.47
0.300 0.72 0.73 0.86 0.53 0.73 0.45
0.313 0.72 0.74 0.87 0.54 0.73 0.46
0.317 0.70 0.74 0.87 0.51 0.73 0.44

*Optimal cut-off value of oxy-hemoglobin, >Optimal cut-off suggests healthy control; <Optimal cut-off suggests the diagnosis of schizophrenia.