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. 2022 Nov 9;8(1):37–50. doi: 10.1016/j.jacbts.2022.07.002

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This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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MIRTH-Induced Changes in Left Ventricular Geometry, Volume, and Ejection Fraction Over 90 Days in Healthy Animals

(A and B) Left ventricular anteroposterior (AP) and septolateral (SL) diameters at the level of MIRTH implant. (C) The impact of basal and midventricular MIRTH (Myocardial Intramural Remodeling by Transvenous Tether) on the interpapillary distance. (D to F) Left ventricular ejection fraction (LVEF) and indexed left ventricular volumes. Data were compared using Wilcoxon signed rank tests. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001. LVEDVI = indexed left ventricular end-diastolic volume; LVESVI = indexed left ventricular end systolic volume.