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. 2023 Jan 2;7(2):264–278. doi: 10.1038/s41559-022-01925-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 6 — The gene structure of ENSG00000205704 was shown, with the items of evidence supporting the transcriptional and translational expression of this new gene aligned accordingly, including the reads density of RNA-seq data of the cortical organoids grown for 60 days (D60 organoids, this study), the reads density of cytoplasmic RNA-seq data of human brain (Human Brain, this study), the Iso-seq reads of human brain (Human Brain by Iso-seq, the same dataset used in validation of ISOR), and the peptides identified by large-scale mass spectrometry (Peptide Evidence, retrieved from PRIDE, PeptideAtlas, ProteomicsDB and Human Proteome Map database).