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. 2023 Jan 2;7(2):264–278. doi: 10.1038/s41559-022-01925-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 2 — a, Western blots showing the protein expression of lamin-B and β-tubulin in nuclear and cytoplasmic fractions from human and macaque cell lines. b, Distributions of the normalized N/C ratios of mRNAs and lncRNAs in HEK293T and LLCMK2 cells. Two-sided, unpaired Wilcoxon test, P value < 2.2e-16, < 2.2e-16, respectively. The boxes represent interquartile range, with the line across the box indicates the median. The whiskers extend to the lowest and the highest value in the dataset. ***P value ≤ 0.001.