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. 2022 Dec 30;20(2):295–303. doi: 10.1038/s41592-022-01711-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Points in plots correspond to optimal thresholds from validation set. Each point represents an ROI. For VOI and MCM, lower scores are better; for ERL, higher scores are better. a, VOI sum versus ROI size (μm³). b, ERL (nanometers) versus ROI size. c,d, MCM sum and VOI sum versus ROI size (first three ROIs), respectively. Dashed line in a corresponds to ROIS shown in c,d. e, TERAFLOPS versus VOI sum across ROIs (as in a,b). f, Mask δ VOI sum versus ROI.

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