Table 1. Clinical isolate pairs.
Inducible isolates with a mutation in sarZ are labeled as I1-I5. Closely related high cytotoxicity isolates that have a WT sarZ locus are labeled H1-H5. Isolates were paired based on relatedness.
| Strain | Pair | Cytotoxicity Classification | Label | sarZ Allele |
|---|---|---|---|---|
| ER00994.3B | 1 | High | H1 | WT |
| ER00594.3B | Inducible | I1 | FS1 | |
| ER00573.3B | 2 | High | H2 | WT |
| ER02658.3B | Inducible | I2 | FS1 | |
| ER06881.3A | 3 | High | H3 | WT |
| ER09970.3A | Inducible | I3 | FS2 | |
| ER05785.3A | 4 | High | H4 | WT |
| ER08181.3B | Inducible | I4 | FS1 | |
| ER04929.3A | 5 | High | H5 | WT |
| ER08597.3A | Inducible | I5 | NS2 |