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. 2023 Feb 9;13:2304. doi: 10.1038/s41598-023-29423-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Treatment with anti-CD36 antibody reduces expression of inflammatory mediators after LPS challenge. (a–x) Protein expression of 24 inflammatory cytokines reveals a significant reduction in cytokines (a) TNF-a, (b) IFN-g, (c) IL-1b, (e) IL-6, (f) IL-10, (h) IL-13, (i) IL-17, along with (k) GCSF, (l) GM-CSF, (m) MCP-1 and chemokines (p) CCL3, (r) CCL11 (s) CCL24, (u) CXCL1, (v) CXCL9 and (x) CXCL13 when the pups are treated with anti-CD36 before LPS. Unpaired t-test ***p ≤ 0.001; **p ≤ 0.01 and *p ≤ 0.05.