TABLE 4.

Multiple linear regression. Stepwise: differences between liver parameter variations and risk factors (p < 0.2).

Variable	GGT variation		AP variation		ALT variation
	B [95% CI]	p	B [95% CI]	p	B [95% CI]	p
Total phytosterols					1.085 [0.358–1.813]	0.006
CRP			0.365 [0.152–0.577]	0.002
IL-10 × total phytosterols	0.085 [0.024–0.145]	0.009			0.093 [−0.011 to 0.198]	0.076
TNF-α × total phytosterols	0.172 [0.073–0.271]	0.002
R 2	0.577		0.435		0.424
CRP			0.365 [0.152–0.577]	0.002	0.137 [0.041–0.233]	0.008
IL-10 × sitosterol	0.121 [0.050–0.193]	0.002
TNF-α × sitosterol	0.159 [0.077–0.240]	0.001
R 2	0.641		0.435		0.347
Lanosterol	0.278 [0.155–0.400]	0.000			0.315 [0.067–0.563]	0.016
CRP			0.365 [0.152–0.577]	0.002
IL-10	0.234 [0.078–0.390]	0.006
R 2	0.662		0.435		0.298
IL-6					0.341 [0.013–0.669]	0.042
IL-6 × campesterol	0.095 [−0.018 to 0.209]	0.095
CRP			0.365 [0.152–0.577]	0.002
CRP × campesterol					0.360 [0.164–0.557]	0.001
IL-10 × campesterol	0.327 [0.030–0.625]	0.033
TNF-α	0.541 [0.006–1.077]	0.048
R 2	0.569		0.435		0.458
Stigmasterol	0.221 [0.100–0.342]	0.001
IL-6 × stigmasterol					0.060 [0.006–0.113]	0.030
CRP			0.365 [0.152–0.577]	0.002
IL-10	0.206 [0.047–0.365]	0.015
TNF-α	0.520 [0.069–0.971]	0.027
R 2	0.690		0.435		0.247

Variables are considered as Napierian logarithm.

CI, confidence interval; GGT, gamma-glutamyltransferase; AP, alkaline phosphatase; ALT, alanine aminotransferase; B, constant in the model R² determination coefficient; CRP, C-reactive protein; IL-6, interleukin-6; IL-10, interleukin-10; TNF-α, tumor necrosis factor-α; Bold means statistically significant.