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. 2023 Jan 27;14:1073407. doi: 10.3389/fphys.2023.1073407

TABLE 2.

Respiratory flux control ratios.

FCR PCR Inv-RCR SCR
BIC Pre 0.78 ± 0.04 0.10 ± 0.03 0.69 ± 0.04
24 h 0.84 ± 0.06 0.10 ± 0.11 0.58 ± 0.16
PLA Pre 0.80 ± 0.05 0.12 ± 0.03 0.64 ± 0.09
24 h 0.73 ± 0.08 0.10 ± 0.03 0.64 ± 0.06

PCR, phosphorylation control ratio (CI + II)Max/(CI + II)ETS;

Inv-RCR, inverse of respiratory control ratio (CI)L/(CI)D5.1;

SCR, substrate control ratio: (CI)D5.1/(CI + II)Max.

FCRs were calculated from mass-specific respiration measurements in permeabilized muscle fibers (vastus lateralis), obtained from muscle biopsies taken before 3 × 30-s Wingate Test and after 24 h of recovery after either BIC (sodium bicarbonate) or PLA (placebo) supplementation (n = 8, Mean ± SD).