Fig. 2. Target definition and 3D-CRT planning recommended in the ARTIST-II trial. Based on the results of locoregional failure studies, secondary and tertiary lymphatic nodes including para-aortic (No. 16a2 to 16b1), celiac (No. 9), hepatoduodenal (No. 12), retropancreatic (No. 13), and superior mesenteric vessel (No. 14) were chosen as RT targets.

3D-CRT = three-dimensional conformal radiotherapy; ARTIST = Adjuvant Chemoradiation Therapy In Stomach Cancer; RT = radiotherapy.