TABLE 5.
Cox regression analysis of the association of ALOX5 and clinical variables with OS in the CGGA-LGG dataset.
| Characteristics (References) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Age | 1.03 (0.99–1.06) | 0.096 | 1.04 (1.01–1.07) | 0.018 |
| Gender (female) | 1.03 (0.57–1.87) | 0.929 | 1.15 (0.61–2.17) | 0.665 |
| IDH status (wild type) | 0.44 (0.23–0.85) | 0.015 | 0.44 (0.21–0.89) | 0.023 |
| Subtype (astrocytoma) | 1.46 (1.02–2.09) | 0.040 | 1.56 (1.10–2.22) | 0.013 |
| ALOX5 | 1.06 (1.03–1.09) | <0.001 | 1.06 (1.03–1.09) | <0.001 |
Abbreviations: OS, overall survival; HR, hazard ratio; 95% CI, 95% confidence interval.