Table 1.

Commercially available radiotherapy platforms specializing in adaptive image-guided and biology-guided radiation therapy.

System	Image guided modality	Real-timeinter-fraction management	Real-timeintra-fraction management	Strengths	Weaknesses
MRIdian	MR (0.35 Tesla)	Yes	Yes, automatically	No ionizing radiations for imaging	Time
				Target visualization during treatment	Coplanar beam fields
				High soft tissue discrimination	No electronic density data
				Functional imaging data
Unity	MR (1.5 Tesla)	Yes	Yes, not automatically	No ionizing radiations for imaging	Time
				Target visualization during treatment	Coplanar beam fields
				High soft tissue discrimination	No electronic density data
				Functional imaging data
Ethos	Artificial Intelligence CT based	Yes	No	Time	Use of ionizing radiations for imaging
					Coplanar beam fields
				Electronic density data	No target visualization during treatment
					Low soft tissue discrimination
					Functional imaging data
RefleXion	PET-CT	Yes	No	Time	Use of ionizing radiations for imaging
				Electronic density data	Coplanar beam fields
				Functional imaging data	No target visualization during treatment
					Low soft tissue discrimination