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. 2023 Jan 27;14:1102778. doi: 10.3389/fimmu.2023.1102778

Figure 5.

Figure 5

Overview of the adoptive T-cell transfer (ACT) approaches to harness the immune system to treat cancer. (A) For TIL ACT, tumor-infiltrating T cells (TILs) are isolated from surgically resected tumor samples and expanded ex vivo. (B) γδT-cell therapy relies on collecting peripheral blood and expanding γδT cells ex vivo. (C) For TCR-T or CAR-T ACT, the peripheral blood T cells are isolated and expressed ex vivo and genetically modified to express either a TCR or a CAR.