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. 2023 Jan 27;14:1078731. doi: 10.3389/fimmu.2023.1078731

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Copyright © 2023 Ji, Pei, Zhang, Lin, Li, Yin, Sun, Su, Qu and Yin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Epilepsy single-cell analysis. (A) Single-cell subpopulation clustering and cell annotation. (B) Three-layered complex heatmap of selected co-expressed genes in each cell cluster. Top: Mean expression of co-expressed markers. Middle: Tissue preference of each cluster; Bottom: Relative expression map of known marker genes associated with each cell subset. Mean expression values are scaled by mean-centering, and transformed to a scale from -2 to 2. (C) Average cell number and relative proportion of subsets from tissues of each origin.