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. 2023 Jan 27;14:1077315. doi: 10.3389/fendo.2023.1077315

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Copyright © 2023 Miao, Zhao, Chen, Wang, Ren, Chen, Dong and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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HSYC decreased oxidative stress of POI afflicted mice. (A) Flow cytometric analysis of ROS accumulation in ovarian granulosa cells of different groups, and histogram plots represents means with SD of median fluorescence intensity (B). (C-F) the levels of serum superoxide dismutase, glutathione peroxidase, malondialdehyde and total antioxidant capacity of mice in different groups. Histogram elements represent the mean ± SD (n=6). ^▲▲ presents P< 0.01 compared to the CON group; ^★presents P < 0.05 compared to the CTX group; ^★★presents P<0.01 compared to the CTX group. SOD, superoxide dismutase; GSH-Px, glutathione peroxidase; MDA, malondialdehyde; T-AOC, total antioxidant capacity.