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. 2023 Jan 27;11:1117954. doi: 10.3389/fbioe.2023.1117954

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Copyright © 2023 Jiao, Hong, Zhang, Wang, Tang, Yang, Qu and Yue.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vitro osteogenic effect of rBMSCs in each porous tantalum scaffold. (A) and (C) Appearance of ALP staining at 7d and 14d. (B) and (D) Quantitative assessment of ALP activity at 7d and 14d of culture. (E) and (G) Appearance of alizarin red staining at 14d and 21d. (F) and (H) Semi-quantitative analysis of alizarin red staining. (I) Osteogenesis-related gene expression at 7d and 14d of culture. Data represent mean ± SD. (n = 3, *p < 0.05; **p < 0.01; ***p < 0.001).