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. 2023 Jan 27;14:1018867. doi: 10.3389/fimmu.2023.1018867

Table 7.

Effects of feeding medium-chain fatty acid on blood metabolites and hormones of pre-calving, early lactation, and peak lactation cows2.

Variable Treatment1 SEM P-value
CON MCFA Treatment Time Treatment×Time
Pre-calving
BHBA3 (mmol/L) 0.48 0.47 0.007 0.62 0.05 0.43
NEFA3 (umol/L) 43.14 41.88 0.586 0.18 <0.01 0.20
TG3 (mmol/L) 0.23 0.20 0.001 0.10 0.05 0.84
INS3 (mIU/mL) 22.65a 18.47b 0.939 0.04 0.32 0.65
Early lactation
BHBA (mmol/L) 0.50 0.50 0.007 0.62 0.01 0.11
NEFA (umol/L) 44.77 43.03 0.593 0.11 0.01 0.14
TG (mmol/L) 0.13 0.13 0.005 0.19 0.62 0.08
INS (mIU/mL) 14.13 14.98 0.681 0.54 0.10 0.41
Peak lactation
BHBA (mmol/L) 0.46 0.44 0.009 0.34 0.97 0.92
NEFA (umol/L) 44.38 43.61 0.688 0.61 0.64 0.69
TG (mmol/L) 0.13 0.15 0.008 0.27 0.16 0.84
INS (mIU/mL) 17.01 18.19 1.028 0.42 <0.01 0.82

SEM, standard error of mean.

a-bMeans within a row with unlike superscripts differ (P ≤ 0.05).

1CON, control treatment, basic diet with no medium chain fatty acids, n = 9. MCFA, MCFA treatment, basic diet and medium chain fatty acids 20 g/d, n = 9.

2Pre-calving, from 21 d before calving to calving, Early lactation = from 1 d to 28 d after calving, Peak lactation = from 29 d to 70 d after calving.

3BHBA, β-hydroxybutyrate; NEFA, non-esterified fatty acid; TG, triglyceride; INS, insulin.