Table 2.

Serum concentrations of immunoglobulin G antibodies to pneumococcal serotypes among 126 infants with sera at birth by HIV exposure status

Serotype	Median (IQR) Serum Antibody Concentration (μg/mL)		p_adj^a
	HEU Infants (n= 35)	HUU Infants (n= 91)
1	0.20 (0.03–0.46)	0.25 (0.03–0.53)	0.59
3	0.31 (0.17–0.49)	0.34 (0.25–0.61) 0.26 (0.12, 0.40)	0.50
4	0.22 (0.11–0.42) 0.03 (0.03, 0.23)	0.26 (0.12–0.40)	0.64
5	0.03 (0.03–0.24) 0.27 (0.21, 0.69)	0.22 (0.05–0.37)	0.046
6A	0.38 (0.28–0.78)	0.70 (0.41–1.13)	0.09
6B	0.27 (0.21–0.69) 0.19 (0.15, 0.54)	0.21 (0.21–0.64)	0.84
7F	0.25 (0.04–0.69)	0.33 (0.15–0.73)	0.06
9V	0.19 (0.15–0.54)	0.30 (0.15–0.72) 1.60 (1.13, 2.82)	0.20
14	1.60 (1.14–2.82) 0.27 (0.07, 0.60)	2.26 (1.22–4.51)	0.39
18C	0.27 (0.07–0.60) 0.79 (0.33, 2.57)	0.40 (0.16–0.91)	0.13
19A	1.46 (0.81–2.08) 0.24 (0.14, 0.83)	1.85 (1.22–3.38) 0.32 (0.14, 0.94)	0.008
19F	0.79 (0.33–2.57)	0.90 (0.33–2.23)	0.66
23F	0.25 (0.14–0.83)	0.32 (0.14–0.94)	0.27

IQR, interquartile range; μg, microgram; mL, milliliter; HEU, HIV-exposed uninfected; HUU, HIV-unexposed uninfected

Adjusted p values were estimated from linear regression models evaluating associations between HIV exposure status and log-transformed serum antibody concentrations and adjusted for infant birth weight and maternal age