Table 1.
The comprassion of the basal demographic and laboratory findings and MLR, PLR, NLR, SII values of patient and control groups
| Patient Group | Control Group(n = 94) | p | |||
|---|---|---|---|---|---|
| Total(n = 186) | Active Lesion( +)(n = 99) | Active Lesion(-)(n = 87) | |||
| Age(year) (mean ± SD) | 33.21 ± 7.6 | 33.85 ± 9.6 | 32.72 ± 7.38 | 33.44 ± 8.04 | b0.656 |
| Gender(female(n,%)) | 141(75.8%) | 73 (73.7%) | 68 (78.2%) | 65 (69.1) | c0.392 |
| Disease Duration(year)(mean ± SD) | 5.05 ± 4.65 | - | - | - | − |
| EDSS(mean ± SD) | 1.11 ± 0.49 | - | - | - | − |
| Lesion count |
1–5: 54 (54.5%) 6–10: 16(16.2%) ≥ 11: 29 (29,3%) |
||||
| Lesion localisation | - |
Supratentorial:77(77.8%) Infratentorial:17(17.2%) Spinal:5(5.1%) |
- | - | − |
|
CRP(mg/dL) (median(min–max)) |
2.3 (0.1–9.8) | 2.1 (0.1–9.8) | 2.4 (0.1–8.5) | 2.4(1–7.1) | b0.425 |
| Monocyte count(109/L) (mean ± SD) | 0.42 ± 0.19 | 0.50 ± 0.23 | 0.42 ± 0.17 | 0.34 ± 0.10 | b 0.001** |
| Lymphocyte count(109/L) (median(min–max)) | 2.2 (0.9–4) | 1.8 (0.9–2.9) | 2.2 (0.9–3.5) | 2.6 (1.4–4) | a 0.001** |
|
Platelet count(109/L) (mean ± SD) |
281.11 ± 69.06 | 330.72 ± 63.74 | 285.92 ± 54.99 | 224.41 ± 36.62 | b0.001** |
| Eosinophil count(109/L) (median(min–max)) | 0.1 (0–0.4) | 0.1 (0–0.4) | 0.1 (0–0.4) | 0.1 (0–0.2) | a0.104 |
| Neutrophil count(109/L) (median(min–max)) | 3.6 (1–14) | 4.2 (2.1–14) | 3.6 (1–14) | 3.1 (1–4.9) | a 0.001** |
| MLR(median(min–max)) | 0.2 (0–1.3) | 0.3 (0.1–1.3) | 0.2 (0–0.7) | 0.1 (0–0.3) | a0.001** |
| PLR(median(min–max)) | 122.8 (43.2–421.8) | 189.8 (83.8–421.8) | 135 (61.3–351.3) | 89.3 (43.2–189) | a0.001** |
| NLR(median(min–max)) | 1.5 (0.4–10.6) | 2.5 (1–10.6) | 1.5 (0.5–10.6) | 1.2 (0.4–2.8) | a0.001** |
| SII(median(min–max)) | 452.7 (71.1–3215.6) | 797.9 (273–3215.6) | 478.1 (151.9–3215.6) | 234.2 (71.1–674) | a0.001** |
EDSS Expanded Disability Status Scale, CRP C- Reactive protein, MLR Monocyte/ lymphocyte ratio, PLR Platelet/ lymphocyte ratio, NLR Neutrophil / lymphocyte ratio, SII Systemic immune-inflammatory index
aKruskal Wallis Test; bOne Way Anova Test; CFisher Freeman Halton Test All values are presented mean ± standard deviation(SD) or median value (min–max); **p<0.05