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. 2023 Feb 10;23:64. doi: 10.1186/s12883-023-03101-0

Table 3.

Diagnostic Screening Tests by presence of active lesions in MS patients and ROC Curve Results for MLR, PLR, NLR, SII

Diagnostic Scan ROC Curve p
Cut off Sensitivite Spesifisite Positive Predictive Value Negative
Predictive Value
Area 95% Confidence Interval
MLR  ≥ 0.183 81.82 91.49 91.00 82.70 0.919 0.881–0.957 0.001**
PLR  ≥ 117.15 91.92 94.68 94.80 91.80 0.967 0.945–0.990 0.001**
NLR  ≥ 1.53 83.84 85.11 85.60 83.30 0.927 0.893–0.961 0.001**
SII  ≥ 434.45 88.89 91.49 91.7 88.7 0.972 0.954–0.989 0.001**

MLR monocyte/ lymphocyte ratio, PLR platelet/ lymphocyte ratio, NLR neutrophil / lymphocyte ratio, SII Systemic immune-inflammatory index

**p<0.05