Table 3.
Associations of actigraphy-estimated sleep and 24-hour activity rhythms with cognitive reserve (n = 1,002)
| Model 1 | Model 2 | Model 3 | |
| Mean difference | Mean difference | Mean difference | |
| (95% CI) | (95% CI) | (95% CI) | |
| Sleep | |||
| Total sleep time, per SD | 0.07 (– 0.02; 0.16) | 0.08 (– 0.01; 0.16) | – 0.02 (– 0.14; 0.10) |
| Sleep efficiency, per SD | 0.14 ( 0.06; 0.22) | 0.14 ( 0.05; 0.22) | 0.10 (– 0.04; 0.25) |
| Sleep onset latency, per SD | – 0.18 (– 0.25; – 0.11) | – 0.16 (– 0.24; – 0.09) | – 0.13 (– 0.21; – 0.04) |
| Wake after sleep onset, per SD | – 0.07 (– 0.15; 0.01) | – 0.06 (– 0.14; 0.02) | 0.02 (– 0.08; 0.13) |
| 24-hour activity rhythms | |||
| Interdaily stability, per SD | 0.10 (0.02; 0.18) | 0.05 (– 0.03; 0.14) | – |
| Intradaily variability, per SD | – 0.08 (– 0.17; 0.00) | – 0.03 (– 0.11; 0.06) | – |
| L5-onset, per SD | 0.06 (– 0.05; 0.18) | 0.06 (– 0.04; 0.17) | – |
Model 1: Unadjusted; Model 2: Adjusted for employment status, body mass index, smoking habits, alcohol intake, coffee consumption, sleep medication, diabetes, hypertension, sleep apnea, depression and time between the cognition, MRI and actigraphy measurements; Model 3: As model 2, but also adjusted for the other sleep variables. All variables within the models have been standardized. Statistically significant results are in bold. CI, confidence interval.