Fig. 2.

Exposures to general anesthetics with trigger agents in carriers of ryanodine receptor 1 mutations. On the vertical and horizontal axes are represented the number of subjects exposed to trigger anesthetics and the total number of exposures, respectively. Exposures in probands (red) include the general anesthetic during which the actual malignant hyperthermia crisis occurred, whereas in family members (green) they comprise the total number of uneventful anesthetics with trigger agents; family members with no anesthetic history (shaded green bar) were excluded from analysis.