Table 1. Baseline characteristics.
| Clinical characteristics | N=37 patients |
|---|---|
| Age, years | 60±8.9 |
| Men, n (%) | 34 (91.9%) |
| Body mass index | 27±5.0 |
| Diabetes mellitus, n (%) | 8 (21.6%) |
| Hypertension, n (%) | 9 (24.3%) |
| Dyslipidaemia, n (%) | 16 (43.2%) |
| Current smoking, n (%) | 9 (24.3%) |
| Positive family history, n (%) | 13 (35.1%) |
| Previous MI, n (%) | 8 (21.6%) |
| Previous PCI, n (%) | 11 (29.7%) |
| LDL (mmol/L) | 2.8 (2.1-3.2) |
| Statin therapy | 20 (54.1%) |
| High-intensity lipid-lowering* | 5 (13.5%) |
| Imaged study vessel characteristics | N=38 vessels |
| LAD, n (%) | 13 (34%) |
| LCX, n (%) | 10 (26%) |
| RCA, n (%) | 15 (39%) |
| Imaged segment length, mm | 50.3 (36.4-58.5) |
| Mean lumen area, mm2 | 8.8 (7.1-11.0) |
| Minimum lumen area, mm2 | 3.9 (2.77-5.05) |
| Mean vessel area, mm2 | 14.9 (11.8-16.4) |
| Percent atheroma volume, (%) | 36.5 (31.3-45.1) |
| Max LCBI4mm | 275.3 (166.7-392.7) |
|
*high-intensity lipid-lowering therapy: rosuvastatin ≥20 mg or atorvastatin ≥40 mg or PCSK9-inhibitor. Data are presented as count and percentage or median and interquartile range. LAD: left anterior descending artery; LCBI: lipid core burden index; LCX: left circumflex artery; LDL: low-density lipoprotein cholesterol; MI: myocardial infarction; PCI: percutaneous coronary intervention; RCA: right coronary artery | |