Table 3. Predictors for radiation dose exposure associated with PCI.
Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|
Effect (95% CI) | p-value | Effect (95% CI) | p-value | ||
Gender, female | –1,390 (–1,414; –1,365) | <0.001 | –1,342 (–1,366; –1,317) | <0.001 | |
Age, per 10 years increase | –50 (–60; –41) | <0.001 | 11 (1; 20) | <0.05 | |
History of CABG | 1,208 (1,168; 1,249) | <0.001 | 1,010 (964; 1,055) | <0.001 | |
Heart failure | 568 (544; 592) | <0.001 | 499 (475; 523) | <0.001 | |
PCI of occluded vessela | 1,224 (1,194; 1,253) | <0.001 | 1,366 (1,334; 1,398 | <0.001 | |
PCI of ostial lesion | 1,131 (1,086; 1,175) | <0.001 | 773 (729; 818) | <0.001 | |
PCI of in-stent stenosis | 20 (–26; 66) | 0.394 | –182 (–226; –137) | <0.001 | |
Coronary artery undergoing PCIb | LAD | Reference | Reference | ||
RCA | 370 (342; 398) | <0.001 | 208 (181; 236) | <0.001 | |
LCx | 317 (285; 349) | <0.001 | 148 (117; 179) | <0.001 | |
Left main | 835 (722; 947) | <0.001 | 515 (404; 625) | <0.001 | |
Bypass graft | 1,222 (1,150; 1,294) | <0.001 | 83 (2; 164) | <0.05 | |
Multivessel PCI | 1,785 (1,748; 1,822) | <0.001 | 1,468 (1,431; 1,505) | <0.001 | |
Site volume, per 100 PCIs increase | 17 (16; 18) | <0.001 | 16 (15; 17) | <0.001 | |
Indication for PCIc | Stable angina | Reference | Reference | ||
ACS (unstable angina, NSTEMI) | 273 (247; 300) | <0.001 | 127 (101; 153) | <0.001 | |
ACS (STEMI) | 206 (172; 240) | <0.001 | –382 (–419; –345) | <0.001 | |
Prognostic indication | 211 (171; 251) | <0.001 | 79 (40; 118) | <0.001 | |
Otherd | 446 (362; 529) | <0.001 | 365 (284; 446) | <0.001 | |
Values are effect (95% CI [confidence interval]). aIncludes PCI of acute and chronic coronary occlusions. bAll targets vs LAD. cAll indications vs stable angina. dIncludes complications after diagnostic catheterisation. The clinical significance level (parameters highlighted by red background and bold characters) was set to a change in the estimated effective dose of 1 mSv (=DAP change of 455 cGy*cm). ACS: acute coronary syndrome; CABG: coronary artery bypass graft; LAD: left anterior descending coronary artery; LCx: left circumflex coronary artery; NSTEMI: non-ST-elevation myocardial infarction; PCI: percutaneous coronary intervention; RCA: right coronary artery; STEMI: ST-elevation myocardial infarction |