Table 3.

Logistic regression of clinical outcomes before and after propensity matching with replacement in daily statin users

Outcomes	Before propensity matching and covariate-adjusted effect size in prehospital statin users (n = 11533)			After propensity matching with replacement and covariate-adjusted effect size in prehospital statin users (n = 11533) (same as Fig. 2)
	OR	(95% CI)	Adjusted P-value	OR	(95% CI)	Adjusted P-value
Primary [no. (%)]
All-cause mortality	0.78	0.73–0.83	<0.001	0.80	0.74–0.86	<0.001
Secondary [no. (%)]
In-hospital mortality from COVID-19 vs. normal or other discharge	0.74	0.69–0.80	<0.001	0.77	0.71–0.84	<0.001
Discharge to hospice vs. normal or other discharge	0.87	0.78–0.98	0.01	0.88	0.80–0.97	0.01
ICU admission	0.84	0.80–0.88	<0.001	0.84	0.79–0.89	<0.001
Severe ARDS with COVID-19 vs. mild/moderate	0.90	0.85–0.96	0.0008	0.89	0.83–0.94	<0.001
Critical ARDS with COVID-19 vs. mild/moderate	0.73	0.67–0.78	<.0001	0.76	0.70–0.83	<0.001
Mechanical ventilation	0.74	0.70–0.79	<0.001	0.77	0.71–0.82	<0.001
Extracorporeal membrane oxygenation	0.29	0.08–1.07	0.06	0.30	0.05–1.57	0.15
Severe sepsis	0.76	0.67–0.86	<0.001	0.78	0.68–0.89	<0.001
Severe sepsis without septic shock	0.73	0.53–1.01	0.06	0.68	0.48–0.96	0.03
Severe sepsis with septic shock	0.76	0.67–0.88	<0.001	0.80	0.67–0.93	0.004
Acute kidney injury	0.90	0.80–1.02	0.10	0.81	0.71–0.93	0.003
Thrombosis	0.59	0.39–0.90	0.01	0.60	0.38–0.93	0.02
Pulmonary embolism	0.89	0.61–1.30	0.55	0.82	0.54–1.23	0.34
Disseminated intravascular coagulation	0.94	0.55–1.58	0.80	0.80	0.74–0.86	<0.001
	Estimate, standard error	(95% CI)	Adjusted P-value	Estimate, standard error	(95% CI)	Adjusted P-value
Hospital length of stay	−0.66, 0.11	(−0.88 to −0.44)	<0.001	−0.66, 0.12	(−0.89 to −0.42)	<0.001
Duration of mechanical ventilation	−1.19, 0.32	(−1.83 to −0.56)	<0.001	−1.27, 0.32	(−1.91 to −0.63)	<0.001

ARDS, acute respiratory distress syndrome; CI, confidence interval; COVID-19, coronavirus disease 2019; OR, odds ratio.