Table 2.
Demographic and baseline characteristics by indication
| Characteristic | cIAI (n = 90) |
cUTI (n = 103) |
HAP/VAP (n = 114) |
Other (n = 209)a |
Total (n = 516) |
|---|---|---|---|---|---|
| Age (years) | |||||
| Mean (SD) | 61.0 (15.9) | 60.7 (18.5) | 59.2 (18.7) | 55.5 (18.8) | 58.3 (18.4) |
| Median | 63.0 | 64.0 | 63.0 | 58.0 | 62.0 |
| Q1, Q3 | 53.0, 70.0 | 46.0, 74.0 | 49.0, 73.0 | 41.0, 71.0 | 45.0, 72.0 |
| Min, max | 19, 90 | 19, 95 | 18, 93 | 18, 98 | 18, 98 |
| Age group, n (%) | |||||
| < 40 | 12 (13.3) | 14 (13.6) | 18 (15.8) | 44 (21.1) | 88 (17.1) |
| 40–49 | 4 (4.4) | 14 (13.6) | 11 (9.6) | 34 (16.3) | 63 (12.2) |
| 50–59 | 17 (18.9) | 15 (14.6) | 19 (16.7) | 32 (15.3) | 83 (16.1) |
| 60–69 | 33 (36.7) | 22 (21.4) | 32 (28.1) | 40 (19.1) | 127 (24.6) |
| 70–79 | 15 (16.7) | 25 (24.3) | 20 (17.5) | 44 (21.1) | 104 (20.2) |
| 80–89 | 8 (8.9) | 8 (7.8) | 11 (9.6) | 12 (5.7) | 39 (7.6) |
| ≥ 90 | 1 (1.1) | 5 (4.9) | 3 (2.6) | 3 (1.4) | 12 (2.3) |
| Gender, n (%) | |||||
| Male | 54 (60.0) | 73 (70.9) | 86 (75.4) | 139 (66.5) | 352 (68.2) |
| Female | 36 (40.0) | 30 (29.1) | 28 (24.6) | 70 (33.5) | 164 (31.8) |
| DCCI score, n (%) | |||||
| 0 | 8 (8.9) | 6 (5.8) | 25 (21.9) | 20 (9.6) | 59 (11.4) |
| 1 | 9 (10.0) | 5 (4.9) | 17 (14.9) | 22 (10.5) | 53 (10.3) |
| 2 | 21 (23.3) | 7 (6.8) | 18 (15.8) | 44 (21.1) | 90 (17.4) |
| 3 | 10 (11.1) | 5 (4.9) | 12 (10.5) | 23 (11.0) | 50 (9.7) |
| ≥ 4 | 42 (46.7) | 80 (77.7) | 42 (36.8) | 100 (47.8) | 264 (51.2) |
| DCCI score | |||||
| Mean (SD) | 4.5 (3.7) | 6.5 (3.8) | 3.4 (3.31) | 4.3 (3.2) | 4.6 (3.6) |
| Median | 3.0 | 6.0 | 2.0 | 3.0 | 4.0 |
| Q1, Q3 | 2.0, 6.0 | 4.0, 9.0 | 1.0, 6.0 | 2.0, 7.0 | 2.0, 7.0 |
| Min, max | 0, 16 | 0, 16 | 0, 14 | 0, 18 | 0, 18 |
| Immunocompromised patients, n (%) | 47 (52.2) | 60 (58.3) | 29 (25.4) | 107 (51.2) | 243 (47.1) |
| Patients with bacteremia, n (%) | |||||
| Primary | – | – | – | 97 (46.4) | 97 (18.8) |
| Secondary | 36 (40.0) | 34 (33.0) | 29 (25.4) | 35 (16.7) | 134 (26.0) |
| No or unknown | 54 (60.0) | 69 (67.0) | 85 (74.6) | 77 (36.8) | 285 (55.2) |
| Infection origin, n (%) | |||||
| Healthcare-associatedb | 30 (33.3) | 41 (39.8) | 15 (13.2) | 30 (14.4) | 116 (22.5) |
| Hospital-acquired | 52 (57.8) | 49 (47.6) | 90 (78.9) | 163 (78.0) | 354 (68.6) |
| Community-acquired | 8 (8.9) | 13 (12.6) | 9 (7.9) | 16 (7.7) | 46 (8.9) |
BSI bloodstream infection, cIAI complicated intra-abdominal infection, cUTI complicated urinary tract infection, HAP hospital-acquired pneumonia, VAP ventilator-associated pneumonia, DCCI Deyo-Charlson Comorbidity Index, Max maximum, Min minimum, Q1 quartile one, Q3 quartile three, SD standard deviation
aIncludes patients with BSI/sepsis
bExcluding hospital-acquired infections