Table 2.
Overall and positive concordance rates and Kappa values describing agreement categories (1 = perfect agreement, 0 = total disagreement). Overall concordance is calculated as (++)+(− −)/total cases, while positive concordance rate is calculated as (++)/((++)+(+ −)).
| Tissue | Overall Concordance Rate % | Positive Concordance Rate % | Kappa (SE) | |||
|---|---|---|---|---|---|---|
| ctDNA | + | − | ||||
| TP53 | + | 10 | 0 | 69.565 | 41.667 | 0.406 (0.107) |
| − | 14 | 22 | ||||
| BRCA1/2 | + | 15 | 0 | 100.000 | 100.000 | 1(0) |
| − | 0 | 31 | ||||
| PI3K pathway | + | 2 | 0 | 91.304 | 33.304 | 0.465 (0.216) |
| − | 4 | 40 | ||||
| Any mutation | + | 15 | 0 | 65.217 | 48.487 | 0.379 (0.098) |
| − | 16 | 15 | ||||