Table 3.
Performance characteristics of uterine lavage mutations for type II ovarian cancer diagnosis comparing type II vs. controls, without the RRS group. PPV—positive predictive value, NPV—negative predictive value.
| Performance of HGSOC vs. other Cases Except for the RSS Group | Sensitivity% | Specificity% | Accuracy% | PPV% | NPV% |
|---|---|---|---|---|---|
| TP53 | 27.03 | 100.0 | 64.94 | 100.0 | 59.70 |
| BRCA1/2 + TP53 | 62.16 | 100.0 | 81.82 | 100.0 | 74.07 |
| BRCA1 | 35.14 | 100.0 | 68.83 | 100.0 | 62.50 |
| BRCA2 | 10.81 | 100.0 | 57.14 | 100.0 | 54.79 |
| PI3K pathway mutations | 2.70 | 87.50 | 46.75 | 16.67 | 49.30 |
| Any gene mutation | 62.16 | 87.50 | 75.32 | 82.14 | 71.43 |