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. 2023 Jan 18;15(3):591. doi: 10.3390/cancers15030591

Table 9.

Pooled pain prevalence, and severity rates by treatment group.

N Studies N cancer Patients Overall Pain
Group 1 18 3294 40.3% (95% CI 30.2–50.4)
Group 2 31 7995 47.8% (95% CI 39.4–56.1)
Group 3 19 8719 54.3% (95% CI 42.0–66.6)
Group 4 32 9118 50.3% (95% CI 42.5–58.0)
Group 5 77 59,766 35.8% (95% CI 31.5–40.1)
Group 6 15 33,162 55.2% (95% CI 39.2–71.3)
Group 7 66 508,827 45.0% (95% CI 39.8–50.1)
Group 8 81 25,832 50.3% (95% CI 44.6–56.1)
Group 9 34 41,881 54.6% (95% CI 43.8–65.5)
Moderate–Severe Pain
Group 1 9 1895 33.1% (95% CI 22.0–44.2)
Group 2 12 5483 27.8% (95% CI 6.7–48.8)
Group 3 11 8057 39.1% (95% CI 30.0–48.1)
Group 4 16 4966 25.2% (95% CI 19.0–31.4)
Group 5 30 24,490 22.8% (95% CI 19.0–26.7)
Group 6 7 35,319 43.3% (95% CI 19.7–66.9)
Group 7 22 107,128 34.2% (95% CI 27.6–40.8)
Group 8 39 18,506 31.0% (95% CI 22.7–39.3)
Group 9 18 43,376 40.7% (95% CI 28.5–52.9)

Group 1: treatment-naïve patients; Group 2: patients receiving curative treatment; Group 3: patients receiving palliative treatment; Group 4: patients receiving curative or palliative treatment, or treatment intent not specified; Group 5: after curative treatment; Group 6: patients without feasible anti-cancer treatment; Group 7: including patients in different phases of treatment; Group 8: patients on anti-cancer treatment; Group 9: patients with advanced, metastatic or terminal disease.