TABLE 4.
Cox's proportional hazards model of cardiovascular disease development as a dependent variable
| Total | NFPG | HFPG | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 95% CI | 95% CI | 95% CI | |||||||||||
| Variables | HR | Lower | Upper | p‐value | HR | Lower | Upper | p‐value | HR | Lower | Upper | p‐value | |
| Model 1 | Female (vs. male) | 0.50 | 0.25 | 1.00 | 0.049 | 0.43 | 0.15 | 1.21 | 0.11 | 0.38 | 0.14 | 1.07 | 0.067 |
| Age (per 1 year) | 1.02 | 0.99 | 1.06 | 0.19 | 1.07 | 1.01 | 1.13 | 0.015 | 0.99 | 0.95 | 1.05 | 0.82 | |
| BMI (per 1 kg/m2) | 1.04 | 0.97 | 1.11 | 0.27 | 1.06 | 0.97 | 1.15 | 0.18 | 1.01 | 0.91 | 1.13 | 0.86 | |
| SBP (per 1 mmHg) | 1.00 | 0.98 | 1.02 | 0.72 | 0.99 | 0.96 | 1.02 | 0.36 | 1.00 | 0.97 | 1.02 | 0.90 | |
| FPG (per 1 mmol/L) | 1.05 | 0.94 | 1.16 | 0.39 | 0.93 | 0.40 | 2.16 | 0.87 | 1.09 | 0.95 | 1.25 | 0.20 | |
| eGFRcys (per 1 ml min−1 [1.73 m]−2) | 0.99 | 0.97 | 1.00 | 0.059 | 1.01 | 0.99 | 1.03 | 0.45 | 0.97 | 0.94 | 0.99 | 0.003 | |
| Model 2 | Female (vs. male) | 0.50 | 0.25 | 0.99 | 0.048 | 0.43 | 0.15 | 1.23 | 0.12 | 0.37 | 0.13 | 1.04 | 0.058 |
| Age (per 1 year) | 1.03 | 1.00 | 1.07 | 0.032 | 1.06 | 1.01 | 1.12 | 0.013 | 1.02 | 0.97 | 1.07 | 0.40 | |
| BMI (per 1 kg/m2) | 1.06 | 0.99 | 1.13 | 0.098 | 1.05 | 0.96 | 1.14 | 0.27 | 1.05 | 0.94 | 1.18 | 0.39 | |
| SBP (per 1 mmHg) | 1.00 | 0.98 | 1.02 | 0.76 | 0.98 | 0.96 | 1.01 | 0.28 | 1.00 | 0.98 | 1.03 | 0.70 | |
| FPG (per 1 mmol/L) | 1.04 | 0.94 | 1.15 | 0.47 | 0.99 | 0.45 | 2.21 | 0.98 | 1.08 | 0.95 | 1.24 | 0.25 | |
| eGFRcr (per 1 ml min−1 [1.73 m]−2) | 0.99 | 0.97 | 1.01 | 0.23 | 1.01 | 0.98 | 1.03 | 0.58 | 0.98 | 0.95 | 1.00 | 0.070 | |
Note: HR indicates the hazard ratio for cardiovascular disease development. Models 1 and 2 include the same independent variables, except for eGFR. p‐values <0.05 are in bold.
Abbreviations: BMI, body mass index; CI, confidence interval; eGFRcys, estimated glomerular filtration rate calculated using serum cystatin C; eGFRcr, estimated glomerular filtration rate calculated using serum creatinine; FPG, fasting plasma glucose; HR, hazard ratio; HFPG, high fasting plasma glucose; NFPG, normal fasting plasma glucose; SBP, systolic blood pressure.