TABLE 5.
Baseline characteristics of patients matched by propensity scores
| Total (n = 72) | Non‐CVD (n = 36) | CVD (n = 36) | p‐value | ||||
|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | ||
| Female (n, %) | 41 | 57 | 25 | 69 | 16 | 44 | 0.032 |
| Age (y) | 55 | 15 | 52 | 17 | 58 | 12 | 0.090 |
| BMI (kg/m2) | 31.4 | 5.6 | 31.9 | 5.3 | 31.0 | 6.0 | 0.52 |
| SBP (mmHg) | 142 | 20 | 143 | 18 | 142 | 22 | 0.93 |
| DBP (mmHg) | 82 | 11 | 82 | 11 | 83 | 11 | 0.70 |
| FPG (mmol/L) | 7.2 | 3.5 | 7.0 | 3.4 | 7.3 | 3.6 | 0.68 |
| HbA1c (mmol/mol) | 52.7 | 15.2 | 52.8 | 14.4 | 52.6 | 16.2 | 0.96 |
| HbA1c (%) | 7.0 | 1.4 | 7.0 | 1.3 | 7.0 | 1.5 | 0.96 |
| IRI (pmol/L) | 138 | 214 | 93 | 65 | 170 | 271 | 0.17 |
| GGT (μkat/L) | 0.80 | 0.76 | 0.85 | 0.83 | 0.76 | 0.69 | 0.63 |
| AST (μkat/L) | 0.46 | 0.21 | 0.50 | 0.24 | 0.42 | 0.16 | 0.096 |
| ALT (μkat/L) | 0.60 | 0.43 | 0.66 | 0.50 | 0.54 | 0.34 | 0.25 |
| TC (mmol/L) | 5.4 | 0.9 | 5.5 | 0.8 | 5.3 | 1.0 | 0.33 |
| HDL‐C (mmol/L) | 1.4 | 0.4 | 1.5 | 0.4 | 1.3 | 0.5 | 0.051 |
| LDL‐C (mmol/L) | 3.3 | 0.8 | 3.3 | 0.8 | 3.2 | 0.8 | 0.45 |
| Triglyceride (mmol/L) | 2.0 | 0.9 | 1.8 | 0.9 | 2.1 | 1.0 | 0.29 |
| hsCRP (mg/L) | 2.82 | 9.56 | 1.77 | 1.81 | 3.87 | 13.41 | 0.36 |
| eGFRcr (mL min−1 [1.73 m]−2) | 79 | 27 | 84 | 28 | 74 | 24 | 0.11 |
| eGFRcys (mL min−1 [1.73 m]−2) | 91 | 28 | 95 | 24 | 88 | 30 | 0.29 |
| Smoking status (n, %) | 0.41 | ||||||
| Ex‐smoker | 9 | 13 | 4 | 11 | 5 | 14 | |
| Current smoker | 14 | 19 | 5 | 14 | 9 | 25 | |
| Antidiabetic agents (n, %) | 29 | 40 | 15 | 42 | 14 | 39 | 0.81 |
| Lipid‐lowering agents (n, %) | 41 | 57 | 16 | 44 | 25 | 69 | 0.032 |
| Antihypertensive agents (n, %) | 38 | 53 | 13 | 36 | 25 | 69 | 0.005 |
| Antiobesity agents (n, %) | 1 | 1 | 0 | 0 | 1 | 3 | 0.31 |
| HFPG (n, %) | 34 | 47 | 15 | 42 | 19 | 53 | 0.35 |
Note: p‐values were obtained using Student's t‐test for continuous variables and the chi‐squared test for categorical variables. p‐values <0.05 are in bold.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CVD, cardiovascular disease; DBP, diastolic blood pressure; eGFRcr, estimated glomerular filtration rate calculated using serum creatinine; eGFRcys, estimated glomerular filtration rate calculated using serum cystatin C; FPG, fasting plasma glucose; GGT, gamma‐glutamyl transferase; HbA1c, hemoglobin A1c; HDL‐C, high‐density lipoprotein‐cholesterol; HFPG, high fasting plasma glucose; hsCRP, high‐sensitivity C‐reactive protein; IRI, immunoreactive insulin; LDL‐C, low‐density lipoprotein‐cholesterol; SBP, systolic blood pressure; SD, standard deviation; TC, total cholesterol.