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. 2023 Jan 18;12(3):357. doi: 10.3390/cells12030357
AIEOP AssociazioneItaliana di Ematologia e OncologiaPediatrica
AIM1 Absent in melanoma 1 protein
ALL Acute lymphoblastic leukemia
AML Acute myeloid leukemia
ANGPTL2 Angiopoietin-like 2
ARPP21 CAMP-regulated phosphoprotein 21
B-ALL B-cell acute lymphoblastic leukemia
BCR::ABL1 BCR and ABL fusion gene
BCR::ABL1-like ALL BCR and ABL fusion gene-like acute lymphoblastic leukemia
BFM Berlin–Frankfurt–Münster
BIRC7 Baculoviral IAP repeat containing 7
BM Bone marrow
BMF Bcl2 modifying factor
BTG1 BTG-anti-proliferation factor 1
CD95 Cluster of differentiation 95
CDKN1A Cyclin-dependent kinase inhibitor 1A
CDKN1B Cyclin-dependent kinase inhibitor 1B
CLIC5 Chloride intracellular channel 5
CNAs Copy number alteration
CNS1 CNS1 = patients with white blood cell count in cerebrospinal fluid < 5 and having no blasts in the cerebrospinal fluid
DLBCL Diffuse large B-cell lymphoma
EBF1 EBF transcription factor 1
EFS Event-free survival
ETS Erythroblast transformation specific
ETV6 ETS variant transcription factor 6
ETV6::RUNX1 ETS variant transcription factor 6 and RUNX family transcription factor 1 fusion gene
ETV6::RUNX1-like ALL ETS variant transcription factor 6 and RUNX family transcription factor 1 fusion gene-like acute lymphoblastic leukemia
ETV6::RUNX1+ ETV6::RUNX1-positive
ETV6::RUNX1− ETV6::RUNX1-negative
FISH Fluorescence in situ hybridization (FISH)
FLT3 Fms-related receptor tyrosine kinase 3
FOXO3A Forkheadbox O3
FPD/AML familial platelet disorder with predisposition to acute myeloid leukemia (FPD/AML)
FRALLE 93 French group for childhood ALL 93 trial (FRALLE 93
GD-ALL-2008 Guangdong Children’s Leukemia Group-ALL-2008
GDP Guanosine diphosphate
GIPFEL Genomic inverse PCR for exploration of ligated breakpoints
GTP Bound and inactive guanosine diphosphate
HLH Helix loop helix
HRAS HRasproto-oncogene, GTPase
HSCs Hematopoietic stem cells
iAMP21 Intrachromosomal amplification of chromosome 21
IGF2BP Insulin-like growth factor 2 mRNA-binding protein
IGF2BP1 Insulin-like growth factor 2 MRNA-Binding Protein 1
IGF2BP2 Insulin-like growth factor 2 MRNA-Binding Protein 2
IGF2BP3 Insulin-like growth factor 2 MRNA-Binding Protein 3
IGH::IL3 Immunoglobulin heavy locus and interleukin 3 fusion gene
IL7R Interleukin 7 receptor
KMT2A lysine methyltransferase 2A
KRAS KRAS proto-oncogene, GTPase
L-ASP L-asparaginase
MDS Myelodysplastic syndrome
MLL-r mixed-lineage leukemia gene rearrangement
MLPA Multiplex ligation probe-dependent amplification
MRD Minimal residual disease
NF1 Neurofibromin 1
NGS Next-generation sequencing
NOPHO Nordic Society of Pediatric Hematology and Oncology
NR3C1 Nuclear receptor subfamily 3 group C member 1
NRAS NRAS proto-oncogene, GTPase
OS Overall survival
PAX5 Paired box 5
PTPN11 Protein tyrosine phosphatase non-receptor type 11
PTPN11 Protein tyrosine phosphatase non-receptor type 11
RAGs Recombination-activating genes
RAS Protein family include
RHD DNA-binding Runt-domain
RT-PCR Reverse transcriptase-polymerase chain reaction
RUNX1 RUNX family transcription factor 1
SPI-B Spi-B transcription factor
SYK Spleen tyrosine kinase
T-ALL T-cell acute lymphoblastic leukemia
TCF3::HLF Transcription factor 3 and HLF transcription factor fusion gene
TCF3::PBX1 Transcription factor 3 and PBX homeobox 1
WBC White blood cell
WBP1L WW domain-binding protein 1-like
WGS/WES Whole genome/whole exome sequencing
WHO-HAEM5 5th edition of the World Health Organization Classification of HaematolymphoidTumours
ZFP423 Zinc finger protein 423