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. 2023 Jan 17;15(3):566. doi: 10.3390/cancers15030566
AC Adjuvant Chemotherapy
ADC Antibody–Drug Conjugates
aaMVAC Accelerated MVAC
Av Avelumab
AZ Atezolizumab
BC Bladder Cancer
CG Cisplatin and Gemcitabine
CI Confidence Interval
CT Chemotherapy
dd-MVAC Dose Dense MVAC
DDR DNA Damage Response
DFS Disease-Free Survival
DUR Durvalumab
EFS Event-Free Survival
EV Enfortumab Vedotin
FGFR Fibroblast Growth Factor Receptor
HER2-ERBB2 Human Epidermal Growth Factor Receptor 2
HIF Hipoxia Inducible Factor
HR Hazard ratio
HRR Homologous recombination repair
ICI Immune checkpoint inhibitor
IDO Indoleamine 2,3-dioxygenase
PARPi Poly ADP-ribose Polymerase inhibitor
irAEs Immune-Related Adverse Events
IT Immunotherapy
KIR Anti-Killer Cell Immunoglobulin-Like Receptor
LAG3 Lymphocyte-activation gene 3
LM Linrodostat Mesylate
m Month
MIBC Muscle-Invasive Bladder Cancer
MVAC Methotrexate, Vinblastine, Doxorubicin and Cisplatin
N Nivolumab
NAC Neoadjuvant Chemotherapy
NLR Neutrophil/Lymphocyte Ratio
ORR Overall Response Rate
pCR Pathological complete response
PEM Pembrolizumab
PGC Paclitaxel, Gemcitabine and Cisplatin
PLND Pelvic Lymph Node Dissection
PD-L1 Programmed Death Ligand 1
PFS Progression-Free Survival
RC Radical Cistectomy
RFS Recurrence-Free Survival
UC Urothelial Cancer
SAE Serious Adverse Event
SG Sacituzumab govitecan
TCGA The Cancer Genome Atlas
TIM-3 T cell immunoglobulin and mucin-domain containing-3
TMB The Mutation Burden
TRAEs Treatment-Related Adverse Events
TROP-2 Tumor-associated calcium signal transducer 2
VEGF Vascular endothelial growth factor
VH Variant Histology
y years