Table 1.
Patient characteristics.
Number of Patients | 571 (n) | 100(%) | ||
---|---|---|---|---|
Male | 326 | 57.1 | ||
Female | 245 | 42.9 | ||
Median Age | 72 years | 63–80 IQRs | ||
Median Age at diagnosis | 66 years | 56–74 IQRs | ||
Median Follow-up | 50.8 moths | 24–97 IQRs | ||
Patient died | Total number | 125 | 21.8 | |
Male | 73 | 58.4 | ||
Female | 52 | 41.6 | ||
Patient “Lost of Follow-up” | Documented | 29 | 5.1 | |
Not documented | 16 | 2.8 | ||
Male | 27 | 60 | ||
Female | 18 | 40 | ||
Initial Performance status | Documentation performed | 534 | 93.5 | |
Normal activity | 145 | 27.2 | ||
Symptoms but fully ambulatory | 248 | 46.4 | ||
Symptoms but in Bed <50% of the day | 46 | 8.6 | ||
Needs to be in bed >50%of the day | 12 | 2.2 | ||
Unable to get out of bed | 3 | 0.6 | ||
ECOG Score | Documentation performed | 534 | 93.5 | |
ECOG 0–2 | 393 | 73.6 | ||
ECOG 3–4 | 141 | 26.4 | ||
Weighted index of comorbidity | Documentation performed | 332 | 58.1 | |
Estimated 10- year survival | points | Number | Percentage | |
98–77 (%) | 0–3 points | 322 | 56.4 | |
53–0 (%) | 4–6 points | 10 | 1.8 | |
Comorbidities | Number | Percentage | ||
Cardiovascular | 26 | 4.5 | ||
Dementia | 4 | 0.7 | ||
COPD | 3 | 0.5 | ||
Connective tissue disease | 0 | 0 | ||
Peptic ulcer | 7 | 1.2 | ||
Diabetes dellitus Diabetes with end organ damage |
30 2 |
5.2 0.35 |
||
Moderate-severe denale disease | 58 | 10.2 | ||
Mild to severe liver disease | 0 | 0 | ||
Hemiplegia | 0 | 0 | ||
AIDS | 0 | 0 | ||
Any other malignancy within the last 5 years Lymphoma Leukaemia Metastatic solid tumor |
19 4 0 0 |
3.3 0.7 0 0 |
||
Neuropathy | 4 | 0.7 | ||
Pain | 34 | 5.9 | ||
CRAB | Documentation performed | 431 | 75.5 | |
1 CRAB Criteria | 313 | 72.6 | ||
2 CRAB Criteria | 65 | 15.1 | ||
3 CRAB Criteria | 40 | 9.3 | ||
4 CRAB Criteria | 13 | 3 | ||
R-ISS III | Documentation performed | 522 | 91.4 | |
R-ISS III | 109 | 19.1 | ||
Cytogenetics | High risk Intermediate/ standard risk Not documented |
124 270 177 |
21.7 47.3 31 |
|
Type of multiple myeloma | Documentation performed | 545 | 95.4 | |
IgG | 304 | 55.8 | ||
IgA | 103 | 17.9 | ||
Free Light Chain | 134 | 23.3 | ||
Other (Asecretory/IgD/E/M) | 4 | 0.7 |