Table 5.
Relative proportions of predominant bacterial taxa in the fecal samples.
| Relative Abundance % (Min–Max) of Sequences | |||
|---|---|---|---|
| Phylum/Class/Order/Family/Genus | HC (n = 12) | IBD (n = 34) | p-Value |
| Actinobacteria | 3.87 (0.02–10.25) | 6.29 (0.26–25.33) | 0.216 |
| Actinobacteria | 0.89 (0.00–4.89) | 0.90 (0.00–9.42) | 0.910 |
| Actinomycetales | 0.02 (0.00–0.10) | 0.27 (0.00–4.04) | 0.105 |
| Actinomycetaceae | 0.02 (0.00–0.10) | 0.27 (0.00–4.04) | 0.105 |
| Actinomyces | 0.01 (0.00–0.07) | 0.13 (0.00–1.38) | 0.058 |
| Corynebacteriales | 0.11 (0.00–0.56) | 0.47 (0.00–8.11) | 0.150 |
| Corynebacteriaceae | 0.11 (0.00–0.56) | 0.47 (0.00–8.11) | 0.150 |
| Corynebacterium | 0.11 (0.00–0.56) | 0.47 (0.00–8.11) | 0.150 |
| Coriobacteriia | 2.97 (0.00–7.21) | 5.39 (0.06–25.17) | 0.165 |
| Coriobacteriales | 2.97 (0.00–7.21) | 5.39 (0.06–25.17) | 0.165 |
| Coriobacteriaceae | 2.78 (0.00–7.21) | 5.19 (0.06–25.17) | 0.173 |
| Collinsella | 2.78 (0.00–7.21) | 5.19 (0.06–25.17) | 0.173 |
| Eggerthellaceae | 0.19 (0.00–0.76) | 0.18 (0.00–0.70) | 0.380 |
| Slackia | 0.18 (0.00–0.68) | 0.15 (0.00–0.70) | 0.262 |
| Bacteroidetes | 13.72 (0.05–38.83) | 8.69 (0.00–26.66) | 0.150 |
| Bacteroidia | 13.72 (0.05–38.83) | 8.69 (0.00–26.66) | 0.150 |
| Bacteroidales | 13.72 (0.05–38.83) | 8.69 (0.00–26.66) | 0.150 |
| Bacteroidaceae | 4.80 (0.02–18.53) | 4.66 (0.00–26.66) | 0.608 |
| Bacteroides | 4.80 (0.02–18.53) | 4.66 (0.00–26.66) | 0.608 |
| Prevotellaceae | 8.76 (0.01–32.38) | 3.59 (0.00–23.53) | 0.005 * |
| Alloprevotella | 1.65 (0.00–4.49) | 1.75 (0.00–18.84) | 0.068 |
| Prevotella | 6.45 (0.00–25.95) | 1.75 (0.00–15.42) | 0.002 * |
| Prevotellaceae Ga6A1 group | 0.65 (0.00–3.85) | 0.10 (0.00–1.48) | 0.006 * |
| Campylobacterota | 2.66 (0.00–21.06) | 5.49 (0.00–40.48) | 0.940 |
| Campylobacteria | 2.66 (0.00–21.06) | 5.49 (0.00–40.48) | 0.940 |
| Campylobacterales | 2.66 (0.00–21.06) | 5.49 (0.00–40.48) | 0.940 |
| Helicobacteraceae | 2.06 (0.00–21–06) | 4.10 (0.00–37.48) | 0.990 |
| Helicobacter | 2.06 (0.00–21–06) | 4.10 (0.00–37.48) | 0.990 |
| Firmicutes | 68.24 (47.44–92.90) | 68.84 (36.09–98.49) | 0.754 |
| Bacilli | 16.91 (2.40–56.31) | 14.71 (1.33–97.87) | 0.774 |
| Erysipelotrichales | 5.76 (1.61–12.24) | 3.23 (0.00–11.15) | 0.019 * |
| Erysipelatoclostridiaceae | 2.43 (0.33–9.68) | 1.31 (0.00–7.02) | 0.062 |
| Candidatus Stoquefichus | 0.13 (0.00–0.41) | 0.01 (0.00–0.30) | <0.001 * |
| Catenibacterium | 1.75 (0.00–9.64) | 0.77 (0.00–6.26) | 0.557 |
| Erysipelatoclostridium | 0.35 (0.00–0.92) | 0.45 (0.00–4.13) | 0.269 |
| Erysipelotrichaceae UCG–003 | 0.20 (0.00–1.00) | 0.08 (0.00–1.57) | 0.061 |
| Erysipelotrichaceae | 3.33 (0.93–6.91) | 1.90 (0.00–9.07) | 0.011 * |
| Allobaculum | 1.70 (0.00–6.73) | 0.48 (0.00–3.95) | 0.003 * |
| Faecalitalea | 0.09 (0.00–0.23) | 0.34 (0.00–2.83) | 0.535 |
| Holdemanella | 0.60 (0.00–2.08) | 0.92 (0.00–8.93) | 0.283 |
| Turicibacter | 0.43 (0.00–3.04) | 0.15 (0.00–1.65) | 0.426 |
| Lactobacillales | 10.78 (0.01–48.68) | 11.14 (0.03–97.13) | 0.189 |
| Enterococcaceae | 0.10 (0.00–0.92) | 4.48 (0.00–96.56) | 0.003 * |
| Enterococcus | 0.10 (0.00–0.92) | 4.48 (0.00–96.56) | 0.003 * |
| Lactobacillaceae | 9.50 (0.00–48.45) | 1.19 (0.00–17.37) | 0.141 |
| Lactobacillus | 9.50 (0.00–48.45) | 1.19 (0.00–17.37) | 0.141 |
| Streptococcaceae | 1.19 (0.00–10.72) | 5.43 (0.00–38.85) | 0.021 * |
| Streptococcus | 1.18 (0.00–10.72) | 5.42 (0.00–38.71) | 0.021 * |
| Staphylococcales | 0.01 (0.00–0.04) | 0.29 (0.00–5.15) | 0.057 |
| Clostridia | 43.31 (26.83–66.44) | 45.58 (0.43–81.79) | 0.754 |
| Clostridiales | 1.08 (0.00–4.21) | 3.52 (0.02–26.67) | 0.643 |
| Clostridiaceae | 1.08 (0.00–4.21) | 3.52 (0.02–26.67) | 0.643 |
| Clostridium sensu stricto 1 | 1.07 (0.00–4.21) | 3.40 (0.01–23.97) | 0.574 |
| Lachnospirales | 21.82 (11.44–37.87) | 27.61 (0.19–67.31) | 0.402 |
| Lachnospiraceae | 21.82 (11.44–37.87) | 27.59 (0.19–67.31) | 0.416 |
| Blautia | 12.59 (6.68–22.93) | 12.85 (0.00–48.68) | 0.476 |
| Lachnoclostridium | 0.51 (0.00–2.07) | 1.99 (0.00–27.09) | 0.489 |
| Lachnospiraceae NK4A136 group | 0.22 (0.00–0.49) | 0.13 (0.00–1.38) | 0.015 * |
| Roseburia | 0.14 (0.00–1.29) | 0.88 (0.00–11.61) | 0.158 |
| [Ruminococcus] gnavus group | 0.66 (0.26–9.87) | 0.47 (0.02–17.48) | 0.767 |
| [Ruminococcus] torques group | 1.54 (0.00–3.95) | 1.16 (0.00–5.94) | 0.101 |
| Sellimonas | 0.27 (0.00–0.73) | 0.17 (0.00–2.66) | 0.042 * |
| Tyzzerella | 0.39 (0.00–1.49) | 0.69 (0.00–5.51) | 0.521 |
| Oscillospirales | 4.40 (0.02–12.67) | 2.76 (0.00–15.46) | 0.037 * |
| Butyricicoccaceae | 0.35 (0.00–1.30) | 0.45 (0.00–7.64) | 0.147 |
| Butyricicoccus | 0.09 (0.00–0.46) | 0.13 (0.00–1.74) | 0.230 |
| Oscillospiraceae | 0.47 (0.00–3.60) | 0.01 (0.00–1.60) | 0.143 |
| UCG–005 | 0.40 (0.00–2.82) | 0.03 (0.00–0.90) | <0.001 * |
| Ruminococcaceae | 3.58 (0.02–8.78) | 2.21 (0.00–14.87) | 0.070 |
| Faecalibacterium | 3.15 (0.00–7.82) | 1.36 (0.00–11.16) | 0.028 * |
| Fournierella | 0.18 (0.00–0.73) | 0.05 (0.00–0.45) | 0.034 * |
| Peptostreptococcales–Tissierellales | 15.69 (3.61–47.54) | 11.56 (0.12–19.06) | 0.124 |
| Peptostreptococcaceae | 15.40 (3.61–47.51) | 11.32 (0.12–36.98) | 0.143 |
| Peptoclostridium | 11.10 (0.01–23.95) | 9.05 (0.00–33.51) | 0.536 |
| Peptostreptococcus | 0.06 (0.00–0.50) | 0.20 (0.00–3.07) | 0.216 |
| Romboutsia | 0.81 (0.00–3.16) | 0.72 (0.00–4.48) | 0.102 |
| Negativicutes | 8.01 (0.004–25.21) | 8.55 (0.00–35.98) | 0.276 |
| Acidaminococcales | 1.64 (0.00–4.34) | 0.58 (0.00–9.67) | 0.001 * |
| Acidaminococcaceae | 1.64 (0.00–4.34) | 0.58 (0.00–9.67) | 0.001 * |
| Phascolarctobacterium | 1.64 (0.00–4.34) | 0.58 (0.00–9.67) | 0.001 * |
| Veillonellales–Selenomonadales | 6.37 (0.004–20.87) | 7.97 (0.00–35.97) | 0.335 |
| Selenomonadaceae | 6.36 (0.004–20.87) | 7.59 (0.00–35.90) | 0.311 |
| Megamonas | 6.36 (0.004–20.87) | 7.59 (0.00–35.90) | 0.311 |
| Fusobacteria | 9.49 (0.64–21.23) | 5.97 (0.00–24.58) | 0.052 |
| Fusobacteriia | 9.49 (0.64–21.23) | 5.97 (0.00–24.58) | 0.052 |
| Fusobacteriales | 9.49 (0.64–21.23) | 5.97 (0.00–24.58) | 0.052 |
| Fusobacteriaceae | 9.49 (0.64–21.23) | 5.97 (0.00–24.58) | 0.052 |
| Fusobacterium | 9.49 (0.64–21.23) | 5.97 (0.00–24.58) | 0.052 |
| Proteobacteria | 2.03 (0.09–8.52) | 4.66 (0.02–30.79) | 0.311 |
| Gammaproteobacteria | 2.03 (0.09–8.52) | 4.66 (0.02–30.79) | 0.311 |
| Aeromonadales | 0.94 (0.00–6.96) | 0.11 (0.00–1.61) | 0.026 * |
| Succinivibrionaceae | 0.94 (0.00–6.96) | 0.11 (0.00–1.61) | 0.026 * |
| Anaerobiospirillum | 0.80 (0.00–6.96) | 0.06 (0.00–1.42) | 0.231 |
| Succinivibrio | 0.15 (0.00–0.78) | 0.05 (0.00–1.43) | 0.031 * |
| Burkholderiales | 0.72 (0.00–1.54) | 0.53 (0.00–3.27) | 0.086 |
| Sutterellaceae | 0.72 (0.00–1.54) | 0.52 (0.00–3.27) | 0.075 |
| Parasutterella | 0.06 (0.00–0.24) | 0.02 (0.00–0.21) | 0.074 |
| Sutterella | 0.66 (0.00–1.52) | 0.50 (0.00–3.06) | 0.275 |
| Enterobacterales | 0.36 (0.00–1.96) | 3.95 (0.00–30.45) | 0.027 * |
| Enterobacteriaceae | 0.24 (0.00–1.95) | 3.91 (0.00–30.45) | 0.008 * |
| Escherichia–Shigella | 0.24 (0.00–1.95) | 3.87 (0.00–30.45) | 0.011 * |
IBD, inflammatory bowel disease; taxa present in at least 50% of the dogs (in any group) were included in this table. * p-value < 0.05 using the Wilcoxon signed-rank test.