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SARS-CoV-2 induces a decrease in the expression of hepatocyte-specific genes. HepaRGdiff cells were infected and incubated in the presence of SARS-CoV-2 for 2 h and expression of albumin (a), cytochromes (CYP) 3A4 (b) and 2C9 (c) was quantified by RT-qPCR 4 d.p.i. The levels were normalized to the levels of GUS mRNA. The values represent the means ± standard deviation (S.D.). * p < 0.05.
