Table 5.
Univariate logistic regression for prediction.
| Univariate Analysis (n LISA = 52; n INSURE = 34) | Odds Ratio (95% Confidence Interval) | SE | p-Value |
|---|---|---|---|
| Need of MV (<72 h) | |||
| LISA (ref. INSURE) | 0.538 (0.212–0.730) | 0.047 | 0.019 * |
| GA, weeks (ref. GA > 26 weeks) | 2.735 (1.608–5.971) | 0.183 | <0.001 * |
| Need for subsequent surfactant doses | |||
| LISA (ref. INSURE) | 0.389 (0.101–0.894) | 0.088 | 0.017 * |
| GA, weeks (ref. GA < 26 weeks) | 2.134 (1.391–5.380) | 0.068 | 0.021 * |
| Morbidity, n (%) | |||
| LISA (ref. INSURE) | 0.492 (0.187–0.892) | 0.049 | 0.015 * |
| GA, weeks (ref. GA > 26 weeks) | 2.821 (1.691–4.976) | 0.065 | 0.026 * |
| Sepsis/probable sepsis, n (%) | |||
| LISA (ref. INSURE) | 0.609 (0.179–0.988) | 0.025 | 0.042 * |
| GA, weeks (ref. GA > 26 weeks) | 3.065 (1.874–6.057) | 0.034 | 0.003 * |
| Deaths, n (%) | |||
| LISA (ref. INSURE) | 0.640 (0.386–0.774) | 0.025 | 0.036 * |
| GA, weeks (ref. GA > 26 weeks) | 5.367 (3.245–7.551) | 0.014 | <0.001 * |
LISA: Less Invasive Surfactant Administration; INSURE: INtubation-SURfactant administration-Extubation; GA: gestational age; * Marked effects are significant at p < 0.05.