Table 1.
C. auris-specific antifungal susceptibility interpretation according to CDC [21].
| Antifungal | MIC | Interpretation |
|---|---|---|
| Fluconazole | ≥32 | Isolates with MIC ≥ 32 were shown to have a mutation of the Erg11 gene |
| Voriconazole | NA | Consider using fluconazole susceptibility as a surrogate for other azoles. Occasionally, isolates that are resistant to fluconazole may respond to voriconazole |
| Amphotericin B | ≥2 | Isolates with a MIC of ≥2 should be considered to be resistant |
| Anidulafungin | ≥4 | Breakpoints are based on the distribution of echinocandin MICs of approximately 100 isolates from diverse geographic locations |
| Caspofungin | ≥2 | |
| Voriconazole | ≥4 |
MIC: minimum inhibitory concentration.