Table 3.
PCOS (n = 28) |
Control (n = 18) |
* p Value | |||
---|---|---|---|---|---|
Groups | Mean (±SD) |
Median (P25–P75) |
Mean (±SD) |
Median (P25–P75) |
|
F/G index (total score) | 14 (±6.6) | 11.5 (8–18) | 5.1 (±0.3) | 5 (4–5) | <0.001 |
Free testosterone e fraction (ng/dL) |
1.3 (±0.6) | 1.1 (0.8–1.7) | 0.4 (±0.2) | 0.3 (0.2–0.5) | <0.001 |
Percentage (%) | 2.0 (±0.5) | 2.0 (1.6–2.4) | 1.8 (±2.3) | 1.3 (1.0–1.7) | <0.001 |
BioavT (ng/dL) 1 | 29.3 (±14.6) | 24.9 (18.6–39) | 6.4 (±5.3) | 6.4 (5.4–12.3) | <0.001 |
Percentage (%) | 47.8 (±11.8) | 47.8 (38.3–56.6) | 29.3 (±10.8) | 28.9 (23.7–37.7) | <0.001 |
SHBG (nmol/L) | 30.3 (±14.7) | 27 (18.8–39) | 71.6 (±45.1) | 58.5 (39.5–76.3) | <0.001 |
Total TESTO (ng/dL) | 62.1 (±29.8) | 57.5 (40.8–72.8) | 28.1 (±8.1) | 26.5 (22–32.8) | <0.001 |
DHEAS (µg/L) | 1910 (±1157.2) | 1713 (856–2528.8) | 1475 (±557.8) | 1477 (1385.8–1572.8) | 0.351 |
A4 (ng/mL) | 1.8 (±0.7) | 1.8 (1.4–2.1) | 1 (±0.4) | 0.9 (0.8–1.2) | <0.001 |
Estradiol(pmol/L) | 70.1 (±42.5) | 65 (40.8–80.4) | 57.6 (±28.3) | 56.5 (35.5–77) | 0.417 |
FSH (mUI/mL) | 4.7 (±1.7) | 4.5 (3.6–6.1) | 6.2 (±1.4) | 6.4 (5.9–7.1) | 0.003 |
LH(mUI/mL) | 9.9 (±4.6) | 9.9 (5.6–12.9) | 5.8 (±2.6) | 5.4 (4.2–6.6) | 0.001 |
PRL (µg/DL) | 15.3 (±5.7) | 14.5 (11–19.8) | 14.9 (±4.9) | 14 (11–18.2) | 0.693 |
* The p value was based on the Mann–Whitney U test; F/G index = Ferriman–Gallwey index. 1 Bioavailable testosterone (ng/dL). DHEAS = dehydroepiandrosterone sulfate; A4 = androstenedione; PRL = prolactin; TESTO = testosterone; SHBG = S = sex hormone binding globulin.