Table 1.
IgG and IgA antibody targets identified in Mtb protein microarray studies
| Rv number | Protein name | Study |
||
|---|---|---|---|---|
| Kunnath-Velayudhan et al. [52, 53] | Deng et al. [54] | Song et al. [55] | ||
| IgG antigen targets | ||||
| Rv3881c | ESX-1 secretion-associated protein EspB | x | x | |
| Rv3804c | Secreted Ag85A/mycolyltransferase | x | ||
| Rv3874 | Secreted antigen Cfp10/EsxB/MTSA-10 | x | ||
| Rv1860 | Secreted glycoprotein 45–47 kDa antigen/MPT32 | x | x | |
| Rv1411c | Lipoprotein LprG | x | ||
| Rv2031c | 16 kDa antigen/alpha-crystallin | x | x | |
| Rv0934 | Glycolipoprotein 38 kDa antigen/PstS1 | x | ||
| Rv3616c | Conserved hypothetical protein | x | ||
| Rv3864 | Conserved hypothetical protein | x | ||
| Rv1980c | Secreted antigen MPT64 | x | ||
| Rv0632c | Enoyl-CoA hydratase/isomerase superfamily | x | ||
| Rv1984c | Secreted antigen Cfp21 | x | ||
| Rv2873 | Surface lipoprotein antigen MPT83 | x | ||
| Rv1174c | Low molecular weight T-cell antigen/TB8.4 | x | ||
| Rv3763 | Lipoprotein lpqH/19 kDa Antigen | x | ||
| Rv0324 | Sulfurtransferase | x | ||
| Rv0537c | Probable integral membrane protein | x | ||
| Rv1685c | Transcriptional regulator, TetR family | x | ||
| Rv2072c | Precorrin-6Y C(5,15)-methyltransferase | x | ||
| Rv3899c | Uncharacterized protein | x | ||
| Rv1100 | Conserved protein | x | ||
| Rv1865c | Oxidoreductase, short-chain dehydrogenase/reductase family | x | ||
| MT0124 | Putative uncharacterized protein | x | ||
| Rv2884 | Probable transcriptional regulator protein | x | ||
| MT3959 | Putative uncharacterized protein | x | ||
| Rv2564 | Uncharacterized ABC transporter ATP-binding protein | x | ||
| Rv1654 | Acetylglutamate kinase | x | ||
| Rv0440 | 60 kDa chaperonin 2 | x | ||
| Rv2853 | PE-PGRS family protein PE_PGRS48 | x | ||
| MT3033 | Uncharacterized protein | x | ||
| Rv3810 | Exported repetitive protein precursor | x | ||
| Rv0109 | E-PGRS family protein PE_PGRS1 | x | ||
| Rv0040c | Secreted proline-rich protein Mtc28 | x | ||
| Rv3260c | Probable transcriptional regulatory protein WhiB-like WhiB2 | x | ||
| Rv1748 | Unknown protein | x | ||
| Rv3835 | Conserved membrane protein | x | ||
| Rv0247c | Probable succinate dehydrogenase | x | ||
| Rv3405c | Possible transcriptional regulatory protein | x | ||
| Rv3822 | Conserved hypothetical protein | x | ||
| Rv2770c | PPE family protein PPE44 | x | ||
| Rv0652 | 50S ribosomal protein L7/L12 RplL | x | ||
| Rv0054 | Single-strand binding protein Ssb | x | ||
| Rv3544c | Probable acyl-CoA dehydrogenase FadE28 | x | ||
| Rv1731 | Possible succinate-semialdehyde dehydrogenase | x | ||
| Rv0178 | Probable conserved Mce associated membrane protein | x | ||
| Rv2306c | Uncharacterized protein Rv2306c | x | ||
| Rv2668 | Possible exported alanine and valine rich protein | x | ||
| Rv3897c | Conserved hypothetical protein | x | ||
| Rv0983 | Probable serine protease PepD | x | ||
| Rv0474 | Probable transcriptional regulatory protein | x | ||
| Rv2831 | Probable enoyl-CoA hydratase EchA16 | x | ||
| Rv3912 | Hypothetical alanine-rich protein | x | ||
| Rv1904 | Conserved hypothetical protein | x | ||
| Rv2922c | Probable chromosome partition protein Smc | x | ||
| Rv2668 | Possible exported alanine and valine rich protein | x | ||
| Rv0638 | Probable preprotein translocase SecE1 | x | ||
| Rv0831c | Conserved protein | x | ||
| Rv1651c | PE-PGRS family protein PE_PGRS30 | x | ||
| IgA antigen targets | ||||
| Rv1411c | Conserved lipoprotein LprG | x | ||
| Rv1754c | Conserved protein | x | ||
| Rv0983 | Probable serine protease PepD | x | ||
| Rv0052 | Conserved protein | x | ||
| Rv2922c | Probable chromosome partition protein Smc | x | ||
| Rv0509 | Probable glutamyl-tRNA reductase HemA | x | ||
| Rv1566c | Possible Inv protein | x | ||