Figure 2.

Ocular phenotype in patients with Ectrodactily-Ectodermal dysplasia Clefting (EEC) syndrome and stages of the pathology. No signs of corneal pannus or inflammatory infiltrates are present in the cornea, which still appears transparent (early stage). Traces of corneal hyperemia and neovascularizazion are starting to be visible, with vessels beginning to invade the cornea. The palisades of Vogt are almost absent (progressing stage). The corneal pannus invades the cornea with neovascularization progressing from both sides of the eye. The palisades of Vogt are absent (middle stage). Keratopathy with dense vascularized corneal pannus and symblepharon of the internal cantus are present. The palisades of Vogt are completely absent (late stage).