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. 2023 Jan 28;12(3):575. doi: 10.3390/foods12030575

Table 1.

Binding constants (Kα) of different carbon atoms of vitamin B12—protein interaction interactions.

Binding Constant—Kα (L/mol)
C20 C25 C35 C53 C10 B10/11 B4 B2 B7
Cyanocobalamin Aqua Cobalamin Cyanocobalamin Aqua Cobalamin Cyanocobalamin Aqua Cobalamin Cyanocobalamin Aqua Cobalamin Cyanocobalamin Aqua Cobalamin Cyanocobalamin Aqua Cobalamin Cyanocobalamin Aqua Cobalamin Cyanocobalamin Aqua Cobalamin Cyanocobalamin Aqua Cobalamin
Gluten 2.88 × 104 3.21 × 104 3.03 × 104 3.59 × 104 3.7 × 103 2.78 × 103 1.99 × 104 4.65 × 103 2.77 × 103 2.83 × 103 3.02 × 104 3.46 × 104 3.16 × 103 3.65 × 103 3.77 × 103 3.09 × 103 2.76 × 103 2.40 × 103
Myoglobin 3.16 × 103 4.04 × 104 4.82 × 104 3.04 × 104 4.34 × 104 4.39 × 104 3.16 × 104 3.51 × 104 4.33 × 104 3.86 × 104 3.96 × 104 4.67 × 104 3.74 × 104 4.86 × 104 3.05 × 104 4.37 × 104 2.48 × 104 4.20 × 104
Casein 4.24 × 104 3.04 × 104 4.88 × 104 2.71 × 104 2.47 × 104 4.27 × 104 3.42 × 104 5.52 × 103 3.01 × 104 3.11 × 104 3.19 × 104 4.72 × 104 2.29 × 104 3.75 × 104 2.92 × 104 3.11 × 104 3.16 × 104 3.04 × 104
Egg albumin 2.35 × 104 3.73 × 104 3.04 × 104 3.20 × 104 2.33 × 104 3.44 × 104 2.43 × 104 2.66 × 104 1.87 × 104 3.28 × 104 1.61 × 104 2.60 × 104 2.48 × 104 4.16 × 104 1.60 × 104 6.46 × 104 2.41 × 104 8.03 × 104
Pea 7.29 × 103 4.10 × 104 2.96 × 104 1.48 × 104 1.13 × 104 3.06 × 104 3.85 × 104 3.04 × 104 1.08 × 104 3.21 × 104 7.65 × 103 3.80 × 104 1.28 × 104 4.54 × 104 1.09 × 104 4.54 × 104 1.01 × 104 4.97 × 104
Rice 3.13 × 104 3.43 × 104 3.84 × 104 2.46 × 104 3.52 × 104 2.46 × 104 2.21 × 104 3.91 × 104 2.44 × 104 2.60 × 104 2.49 × 104 4.28 × 104 2.01 × 104 2.41 × 104 2.31 × 103 2.56 × 103 4.81 × 104 2.95 × 104