Table 5.
IC50 values of inhibitory effects of valerian extracts against pancreatic lipase, angiotensin converting enzyme, α-amylase, and α-glucosidase.
| Extraction Method | IC50 Values (mg Extract/mL) 1 | |||||||
|---|---|---|---|---|---|---|---|---|
| Pancreatic Lipase | ACE 2 | α-Amylase | α-Glucosidase | |||||
| Roots | Rhizomes | Roots | Rhizomes | Roots | Rhizomes | Roots | Rhizomes | |
| 75C0E | 50.75 ± 0.56A 3 | 88.05 ± 1.69A | 13.66 ± 0.52A | 14.11 ± 0.43A | 32.32 ± 0.54A | 42.36 ± 0.24A | 26.94 ± 0.58A | 21.80 ± 2.05A |
| 75C25E | 41.84 ± 0.74B | 82.38 ± 1.00B | 11.22 ± 0.13B | 12.52 ± 0.16B | 30.41 ± 0.59B | 35.47 ± 0.15B | 25.92 ± 0.40B | 19.28 ± 0.46B |
| 75C50E | 38.28 ± 1.40C | 47.34 ± 0.99C | 4.24 ± 0.10C | 4.71 ± 0.06C | 28.23 ± 0.48C | 29.19 ± 0.86C | 18.46 ± 0.69C | 18.86 ± 0.13B |
| 75C75E | 30.67 ± 0.23D | 44.18 ± 0.25D | 4.02 ± 0.02C | 4.86 ± 0.10C | 20.65 ± 0.39D | 25.16 ±0.49D | 17.99 ± 0.44C | 18.59 ± 0.21B |
| 75C95E | 17.59 ± 0.82E | 40.92 ± 0.54E | 3.75 ± 0.09C | 4.87 ± 0.10C | 12.53 ± 0.10E | 21.99 ± 0.27E | 15.40 ± 0.35D | 17.10 ± 1.02C |
1 IC50 value: The enzyme activity was inhibited by 50%. The IC50 value was obtained by interpolation from linear regression analysis. 2 ACE: Angiotensin converting enzyme. 3 Each value is expressed as mean ± standard deviation (n = 4). Means with different capital letters within a column differ significantly (p < 0.05).