Table I.

SNVs identified by the three variant-calling pipelines GATK, SAMtools and VarScan 2.

Type of SNV	Chromosome	Position	dbSNP138	Y/H	O/L	GATK	SAMtools	VarScan 2
Synonymous	chr17	8 108 190	Yes	1	0	No	No	Yes
Non-synonymous	chr17	8 108 331	Yes	165	149	Yes	No	No
Synonymous	chr17	8 108 339	Yes	128	110	Yes	Yes	Yes
Synonymous	chr17	8 108 552	No	77	87	Yes	No	No
Synonymous	chr17	8 108 690	No	94	83	Yes	No	No
Synonymous	chr17	8 109 901	Yes	0	1	Yes	Yes	No
Synonymous	chr17	8 110 622	Yes	1	0	Yes	No	No
Non-synonymous	chr17	8 111 091*	No	0	1	Yes	Yes	No
Non-synonymous	chr19	57 743 531*	Yes	1	0	Yes	Yes	Yes
Synonymous	chr19	57 744 009	Yes	1	0	Yes	No	No

Chromosome 17 contains AURKB and Chromosome 19 contains AURKC.

Y/H, Number of alternative alleles in the young patient; high aneuploidy rate. O/L, Number of alternative alleles in the old patient, low aneuploidy rate; SNV, single nucleotide variant.

*Indicates the SNVs further studied in this report.