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[Preprint]. 2023 Feb 2:2023.01.30.526315. [Version 1] doi: 10.1101/2023.01.30.526315

Figure 5: Structural characterisation of rsVLPs.

Figure 5:

Depiction of different conformations observed with NAg to HAg shift, and the loss of pocket factor. Cartoon and stick representation of the native conformation (PDB-3VBS), expanded conformation (PDB-3VBU) and rsVLP (major population) focusing upon the region surrounding the canyon and pocket. Residues associated with EC VLP stabilisation in rsVLPs are highlighted: VP3 I325M, VP1 Y116C, VP1 K162I, and the interacting residues VP1 D110, and VP3 D183. Some regions of the capsid have been clipped for clarity.