Figure 1.

Expected versus actual counts of mutations. (A) The number of expected counts of each type of nucleotide mutation is computed from four-fold degenerate sites, and then compared the actual counts of each mutation. (B) Expected versus actual counts for each nucleotide mutation type aggregated across all viral clades and averaged across all sites where the mutation is four-fold degenerate, synonymous (including four-fold degenerate), nonsynonymous, or introduces a stop codon. See https://jbloomlab.github.io/SARS2-mut-fitness/avg_counts.html for an interactive version of panel B that enables mouseovers to read off specific values.